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21.
王文佳  熊涓 《企业经济》2020,(1):108-118
通过空间计量模型考察生产性服务业发展模式与制造业集聚的空间溢出效应后发现:生产性服务业专业化水平及多样化水平与制造业集聚呈倒U型关系,同时城市化水平会对服务业发展模式与制造业集聚关系产生影响。分区域模型研究发现,生产性服务业对制造业全要素生产率影响因区域经济发展水平、产业层次、要素禀赋等因素有所差异,东部地区制造业全要素生产率与生产性服务业呈线性关系,适合选择多样化发展模式;中部地区呈倒U型关系,现阶段中部地区生产性服务业更适合选择多样化发展模式;西部地区生产性服务业发展水平与制造业全要素生产率呈正U型关系,生产性服务业专业化和多样化发展都将促进制造业全要素生产率提升。  相似文献   
22.
Background: Inhibitor development to factor VIII (FVIII) hemophilia therapy results in increased complications and substantial economic costs. The SIPPET study, the first randomized controlled trial to compare the immunogenicity of plasma-derived FVIII (pdFVIII)/von Willebrand factor (VWF) and recombinant-DNA-derived FVIII (rFVIII), demonstrated higher inhibitor rates in previously untreated patients (PUPs) treated with rFVIII than in PUPs treated with pdFVIII/VWF.

Objective: To quantify the economic impact of treating PUPs with pdFVIII/VWF vs rFVIII.

Methods: An Excel-based clinical and economic model was developed from a US healthcare payer perspective and run over a 5-year period. The analysis utilized a cohort approach to model patient treatment and outcomes over a monthly cycle to quantify differences in costs of FVIII, bypassing agents, and hospitalizations for serious bleeds. Rates of high-titer inhibitor development were obtained from the SIPPET study. Patients developing high-titer inhibitors were treated with immune tolerance induction (ITI). Patients who developed low-titer inhibitors and those who did not develop inhibitors continued their usual FVIII treatment. Patients who were successfully treated with ITI returned to FVIII treatment, while unsuccessfully treated patients received bypassing agents. Total costs per treated patient were estimated and a one-way sensitivity analysis was conducted to quantify the impact of parameter uncertainty on the model outcomes.

Results: Total cumulative costs per patient over 5 years were $834,621 for pdFVIII/VWF patients and $1,237,163 for rFVIII patients, representing a total saving of $402,542 per patient over the 5-year period, for an average annual saving of $80,508 per patient.

Conclusions: Based on data from the SIPPET study, this analysis found that initiating FVIII treatment in severe hemophilia A PUPs with pdFVIII/VWF has the potential to offer substantial cost savings to healthcare payers, amounting to a one-third reduction in costs.  相似文献   
23.
经济社会转型期典型的中国式"压力型"财政,对地方创新活动和绿色可持续发展具有重要影响。运用2004~2017年中国256个地级市面板数据,实证考察了财政压力对绿色全要素生产率的影响以及传导机制。基准检验结果显示,财政压力显著抑制了绿色全要素生产率的提升,技术创新对绿色全要素生产率具有显著的促进作用;中介效应检验发现,财政压力通过抑制技术创新进而阻碍绿色全要素生产率的提升,即验证了财政压力→技术创新→绿色全要素生产率的传导机制;进一步门槛效应检验表明,技术创新对绿色全要素生产率的影响存在基于财政压力的双门槛效应,在财政压力的不同门槛值区间,技术创新对绿色全要素生产率的促进效应呈现出明显的阶梯性降低趋势。未来需综合完善中国式"压力型"财政激励制度,合理控制财政压力的区间范围,助力技术创新以提升城市绿色全要素生产率。  相似文献   
24.
In this study, we examine the effects of four demographic factors, namely, birth, death, natural aging, and net migration, on population aging and income inequality in China. We use the official Chinese data and the China Household Income Project Survey data for the 2007–2013 period and apply a decomposition model based on the Shapley method. Unlike previous studies, we include migration in our decomposition model and find that natural aging is the primary factor contributing to population aging in both urban and rural areas. Further, migration may accelerate population aging in rural areas. Moreover, migration contributes to reducing income inequality in urban areas, while widening income inequality in rural areas. The effect of migration is larger than those of birth, death, and natural aging on income inequality. The robustness checks confirm these conclusions.  相似文献   
25.
Dynamic factor models have been the main “big data” tool used by empirical macroeconomists during the last 30 years. In this context, Kalman filter and smoothing (KFS) procedures can cope with missing data, mixed frequency data, time-varying parameters, non-linearities, non-stationarity, and many other characteristics often observed in real systems of economic variables. The main contribution of this paper is to provide a comprehensive updated summary of the literature on latent common factors extracted using KFS procedures in the context of dynamic factor models, pointing out their potential limitations. Signal extraction and parameter estimation issues are separately analyzed. Identification issues are also tackled in both stationary and non-stationary models. Finally, empirical applications are surveyed in both cases. This survey is relevant to researchers and practitioners interested not only in the theory of KFS procedures for factor extraction in dynamic factor models but also in their empirical application in macroeconomics and finance.  相似文献   
26.
Online-to-offline (O2O) has become a rapidly growing e-commerce model worldwide, but the factors influencing consumers' purchase decision-making have not been examined well. After exploring the working mechanism of the O2O model, we extract eleven indexes of consumers' overall evaluation in the O2O model with Crawlzilla and R techniques. Social network analysis (SNA) is adopted to build social networks reflecting consumers' overall evaluation in the O2O model. Based on the modified social network and the extracted subgraph, this study (N = 768) reveals consumers' overall evaluation behavior patterns in the O2O model by calculating network density, central potential, edge betweenness. The results show that shoppers overall evaluate the eleven indexes, especially perceived product quality, online product price, promotion intensity, business reputation, and product brand, which reflects the significant associations between the indexes. Among all the eleven evaluation indexes, perceived product quality, online product price, and business reputation dominate consumers’ decision-making behavior. When making purchase decisions, consumers not only overall consider online product price, perceived product quality, and business reputation but also balance perceived product quality, business reputation, and promotion intensity. Finally, we make some suggestions on marketing strategy for e-commerce companies.  相似文献   
27.
This paper proposes an empirical model for analysing the dynamics of Bitcoin prices. To do this, we consider a vector error correction model over two overlapping periods: 2010–17 and 2010–19. Price discovery is achieved through the Gonzalo–Granger permanent‐transitory decomposition. The pricing factors are endogenous linear combinations of the S&P 500 index, gold price, a Google search variable associated to Bitcoin and a fear index proxied by the FED Financial Stress Index. Our empirical analysis shows that during the first period, a linear combination of four pricing factors describes the efficient Bitcoin price. The S&P 500 index and Google searches have a positive effect whereas gold prices and the fear index have a negative effect. In contrast, during the second period, the efficient price behaves idiosyncratically and can be only rationalised by individuals' search for information on the cryptocurrency. These findings provide empirical evidence on the presence of a correction in Bitcoin prices during the period 2018–19 uncorrelated to market fundamentals. We also show that standard empirical asset pricing models perform poorly for explaining Bitcoin prices.  相似文献   
28.
This paper investigates whether climatic adjusted total factor productivity (CATFP) in Latin America and the Caribbean (LAC) is converging, converging to different steady states or exhibit absolute convergence, that is the process does not require (government) interventions to reach its equilibrium path. We use data from the University of East Anglia’s Climatic Research Unit and from the Food and Agriculture Organization for 28 LAC countries over a 54‐year period (1961–2014) to estimate random parameters stochastic production frontier models to calculate CATFP and then use cross‐sectional regressions and an error correction model to analyse CATFP convergence across countries in the region. The results show that technological progress is the main driver of CATFP growth in the region and there is no absolute convergence, that is CATFP gaps across countries will not decrease over time and least performing countries will not grow faster than better performing ones without targeted policies. However, CATFP across LAC exhibits conditional convergence towards different steady states. Technological progress plays a critical role in raising the steady state level of CATFP with an overall average of 2.22 per cent per annum.  相似文献   
29.
This study explores the conditional version of the capital asset pricing model on sentiment to provide a behavioural intuition behind the value premium and market mispricing. We find betas (β) and the market risk premium to vary over time across different sentiment indices and portfolios. More importantly, the state β derived from this sentiment-scaled model provides a behavioural explanation of the value premium and a set of anomalies driven by mispricing. Different from the static β–return relation that gives a flat security market line, we document upward security market lines when plotting portfolio returns against their state βs and portfolios with higher state βs earn higher returns.  相似文献   
30.
为提升大数据技术在农业领域的应用深度与广度,进一步挖掘农业数据资源,推动农业供给侧改革。基于189份农业企业调研数据,运用ISM模型,分析了农业企业采纳大数据技术影响因素及其关联关系与递阶层次结构。提出加大技术的研发力度,提高核心设备和技术的自主知识产权水平,加强大数据技术产业协作,培养企业数据管理意识与大数据技术型人才,加强大数据技术公共示范工程的宣传作用等对策建议。  相似文献   
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